발간년도 : [2023]
| 논문정보 |
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| 논문명(한글) |
[Vol.18, No.3] Analysis of Papers on Side-Effects Caused by Herbal Medicine Prescription Using Text Mining: Leveraging PubMed Articles |
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| 논문투고자 |
Sang-Jun Yea |
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| 논문내용 |
Herbal medicine prescription which is generally derived from natural ingredients in plants and animals is perceived to have a mild effect and relatively safe, but like all other drugs, the possibility of side-effects exists as the efficacy of the active ingredient is manifested through the processes of absorption, diffusion, metabolism, and excretion. It is known that knowing the information about the side-effects of drugs in advance is very helpful in preventing side-effects, but analysis studies on side-effects caused by herbal medicine prescription are not actively conducted. In this study, therefore, we sorted out 24 papers related to side-effects of herbal medicine prescription by text mining articles from PubMed in order to grasp the current status of side-effects caused by herbal medicine prescription. From the analysis of selected papers, we found that studies on the side-effects of herbal medicine prescription were concentrated on side-effects caused by sosiho-tang until the late 1990s, and since 2000, papers on side-effects caused by other herbal medicine prescription have been published. Thirteen types of herbal medicine prescription were reported in the 24 papers selected in this study, and the herbal medicine prescription with the most reported side-effects was sosiho-tang, with nine case reports. Pneumonitis accounted for the largest proportion of side-effects caused by herbal medicine prescription at 61%, followed by hypoxemia and hemorrhage. The symptoms of side-effects reported by patients were mainly cough (26%), dyspnea (26%), and fever (23%), and other symptoms such as phlegm and pyuria were also reported. |
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